PHILADELPHIA -- Cole Hamels threw seven sharp innings to earn his 100th career win, Domonic Brown had a career-best five RBIs and the Philadelphia Phillies beat the Cincinnati Reds 12-1 on Saturday night to end a four-game losing streak.
Hamels (1-2) didn't need much run support.
Coming off a career-high 133-pitch outing at the Mets last Sunday, the three-time All-Star left-hander was impressive. Hamels gave up one run and three hits, striking out 10 on 90 pitches.
Hamels, the 2008 World Series MVP, was stuck on 99 wins since last Sept. 14. He improved to 9-0 against the Reds, including the postseason. The Phillies are 12-0 when Hamels starts vs. Cincinnati.
Homer Bailey (3-3) gave up six runs and seven hits in 3 2/3 innings.
Phillies manager Ryne Sandberg used his 23rd different lineup in 40 games. Jimmy Rollins led off for the second straight game instead of Ben Revere, who has a stomach virus. Asche moved up to sixth from eighth and Brown was dropped to seventh from sixth.
Brown followed with a two-run shot into the second deck in right field. Brown got a green light on a 3-0 pitch and didn't miss it, connecting for only his second homer in 234 at-bats, dating to last season. Brown led the Phillies with 27 homers in 2013 and was an NL All-Star in his first full season in the majors.
Asche had an RBI single in the seventh, Brown followed with a three-run double and John Mayberry Jr. snapped an 0-for-14 slump with an RBI double.